Integrating multiple key molecules in uveal melanoma to uncover metastatic and immune microenvironment-related gene signatures
This study establishes and validates a seven-gene signature associated with metastasis and prognosis in UVM. The findings provide a framework for understanding molecular determinants of tumor progression and immune microenvironment alterations, and may offer guidance for future mechanistic studies and therapeutic exploration.
Authors
- Ying Han (ORCID: https://orcid.org/0000-0003-3046-9507)
- Jiaqi Wang (ORCID: https://orcid.org/0000-0003-4765-7221)
- Yang Liu (ORCID: https://orcid.org/0000-0001-6747-9069)
- Juan Huang (ORCID: https://orcid.org/0000-0002-5330-8338)
- Yiming Guo
- Ye Lu (ORCID: https://orcid.org/0009-0009-4948-9680)
- Jun-Han Wei (ORCID: https://orcid.org/0000-0002-9930-0243)
Institutions
- Northwest University (CN)
- Shanxi Eye Hospital (CN)
Publication Details
- Journal
- International Journal of Ophthalmology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.18240/ijo.2026.01.02
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00