Intraocular inflammation after intravitreal injection of faricimab–a case series including one case of bilateral choroidal involvement
Sterile IOI after faricimab appears to be a rare but relevant adverse event. Although the incidence falls within expected ranges for anti-vascular endothelial growth factor (anti-VEGF) agents, the observed choroidal involvement represents a potentially new safety signal. Prompt diagnosis and corticosteroid therapy are effective in all cases. Our findings support the need for vigilant post-marketing surveillance and further studies to better understand the underlying mechanisms and risk factors of faricimab-associated inflammation.
Authors
- Michal Koubek (ORCID: https://orcid.org/0000-0003-0259-5776)
- Teresa Rauchegger (ORCID: https://orcid.org/0000-0003-3439-6333)
- Matúš Rehák (ORCID: https://orcid.org/0000-0002-3257-6181)
- Yvonne Nowosielski (ORCID: https://orcid.org/0000-0002-2244-8645)
- Gertrud Haas (ORCID: https://orcid.org/0000-0002-0154-3280)
- Roman Lischke
Institutions
- Innsbruck Medical University (AT)
- Charles University (CZ)
- University Hospital Ostrava (CZ)
Publication Details
- Journal
- International Journal of Ophthalmology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.18240/ijo.2026.01.23
- Citations
- 1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.71