Efficacy of intradiscal autologous platelet-rich plasma injection in chronic lumbar disc prolapse: A quasi-experimental study
Intradiscal PRP injection significantly improved pain and function in patients with lumbar disc disease, with clinical improvements that approached the level observed in physiotherapy responders, despite baseline differences in symptom severity. PRP shows promise as an effective treatment for lumbar disc pathology; however, these preliminary findings are limited by the small sample size and short follow-up, warranting larger trials with long-term evaluation.
Authors
- Prabu Mounisamy
- Sathish Muthu (ORCID: https://orcid.org/0000-0002-7143-4354)
- Dibyajyoti Sahoo
- Swaminathan Ramasubramanian (ORCID: https://orcid.org/0000-0001-8845-8427)
- Madhan Jeyaraman
- Naveen Jeyaraman
- Anirudh Dwajan
Institutions
- Dr. M.G.R. Educational and Research Institute (IN)
- Meenakshi Academy of Higher Education and Research (IN)
- ACS Medical College and Hospital (IN)
- Institute for Stem Cell Biology and Regenerative Medicine (IN)
- Orthopaedic Research Group (IN)
- Meenakshi Medical College Hospital and Research Institute (IN)
- Regenerative Medicine Institute (MX)
Publication Details
- Journal
- World Journal of Orthopedics
- Published
- 2025-12-17
- DOI
- https://doi.org/10.5312/wjo.v16.i12.110530
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00