Association of homologous recombination repair gene mutation with clinical prognosis in histological subtypes of epithelial ovarian cancer patients
HRR gene mutations were associated with platinum sensitivity, PARPi response and favorable survival in serous EOC patients. In non-serous EOC, HRR gene mutations did not show the same trend, which warrants further investigation.
Authors
- Kuan‐Ting Kuo (ORCID: https://orcid.org/0000-0002-3657-1652)
- Yi‐Jou Tai (ORCID: https://orcid.org/0000-0003-1442-0850)
- Yen-Han Wang (ORCID: https://orcid.org/0009-0001-9363-3055)
- Ying‐Cheng Chiang (ORCID: https://orcid.org/0000-0002-8958-5222)
- Po‐Han Lin (ORCID: https://orcid.org/0000-0001-6066-398X)
- Chia‐Ying Wu (ORCID: https://orcid.org/0000-0001-9431-5916)
- Heng‐Cheng Hsu (ORCID: https://orcid.org/0000-0002-6817-0693)
Institutions
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Journal of Gynecologic Oncology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3802/jgo.2026.37.e35
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00