Preventing resistance development in infections by OXA β-lactamase-producing <i>Pseudomonas aeruginosa</i> : correlating clinical outcomes with hollow-fibre model input
These findings underscore the importance of optimized dosing strategies, particularly high-concentration and prolonged infusions, in eradicating and preventing resistance development in OXA-producing P. aeruginosa infections.
Authors
- Xavier Mulet (ORCID: https://orcid.org/0000-0001-6297-8256)
- Juan Pablo Horcajada (ORCID: https://orcid.org/0000-0001-9873-5459)
- Sara Cortés-Lara
- Inmaculada López-Montesinos (ORCID: https://orcid.org/0000-0002-2675-4412)
- Sònia Luque (ORCID: https://orcid.org/0000-0002-3215-320X)
- Antonio Oliver (ORCID: https://orcid.org/0000-0001-9327-1894)
- Silvia Castañeda
- Luisa Sorlí (ORCID: https://orcid.org/0000-0001-9562-514X)
- Sandra Domene-Ochoa (ORCID: https://orcid.org/0000-0003-4315-9794)
- M. Montero (ORCID: https://orcid.org/0000-0001-5991-6804)
- Carla López-Causapé (ORCID: https://orcid.org/0000-0003-2228-2005)
- Eduardo Padilla (ORCID: https://orcid.org/0000-0002-3960-8641)
- Almudena Fernández-Muñoz
- Maria Asunción Colomar
Institutions
- Generalitat de Catalunya (ES)
- Universitat Pompeu Fabra (ES)
- Instituto de Salud Carlos III (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Del Mar (ES)
- Hospital Universitario Son Espases (ES)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1093/jac/dkaf464
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00