Cutaneous and Genitalia Inflammation Treated With Guselkumab and Antimicrobial Therapy in a Patient with a History of Crohn's Disease
Cutaneous Crohn's disease (CD) is a rare manifestation of inflammatory bowel disease characterized by cutaneous lesions that are noncontiguous with gastrointestinal tissue yet share similar histopathologic features with gastrointestinal CD. To our knowledge, there are no published data on the use of guselkumab for cutaneous CD. We discuss a case of concomitant pyoderma gangrenosum and cutaneous CD treated with a novel combination of guselkumab, antimicrobial agents, and corticosteroids.
Authors
- Joel Pekow
- Surya Khadilkar
- David T. Rubin (ORCID: https://orcid.org/0000-0001-5647-1723)
- Kelsey Gradwohl (ORCID: https://orcid.org/0000-0003-0824-3608)
- Newsha Nikzad (ORCID: https://orcid.org/0000-0001-8447-8527)
- Angad Chadha (ORCID: https://orcid.org/0000-0001-7986-3244)
- Oluwakemi Onajin Darkwa
Institutions
- University of Illinois Chicago (US)
- University of Chicago (US)
Publication Details
- Journal
- ACG Case Reports Journal
- Published
- 2025-12-01
- DOI
- https://doi.org/10.14309/crj.0000000000001936
- Primary Topic
- Autoimmune and Inflammatory Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00