Vitamin K1 Induced Cytotoxic Effects and Transcriptomic Analysis in Jurkat T Lymphocyte Leukemia Cells
VK1 has cytotoxic effects and transcriptional regulation of multiple genes on Jurkat T cells. The genes of <i>HMGCR</i> and <i>HMGCS1</i> related pathways may play roles in this process.
Authors
- Xiaotong Lou (ORCID: https://orcid.org/0000-0003-1480-3667)
- Xin‐Lou Li (ORCID: https://orcid.org/0000-0002-7743-0856)
- Yaya Qin (ORCID: https://orcid.org/0000-0001-9656-2910)
- Ying Shang (ORCID: https://orcid.org/0009-0009-9254-6521)
- Hongjiang Wang (ORCID: https://orcid.org/0000-0003-2763-3089)
- Shujun Song (ORCID: https://orcid.org/0000-0003-2121-5679)
- Yingying Wu (ORCID: https://orcid.org/0000-0002-5289-833X)
- Xiaoyu Ma (ORCID: https://orcid.org/0009-0004-0665-5953)
- Shaoyan Si
Institutions
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/cmar.s550692
- Primary Topic
- Vitamin K Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00