Analgesic Efficacy and Tolerability of Amitriptyline versus Mianserin in Chronic Low Back Pain: A Randomised, Double-Blind, Controlled Pilot Trial
Both amitriptyline and mianserin appear to provide comparable adjunctive efficacy for CLBP. Mianserin may be more tolerable and cost-effective in resource-limited settings, although it is not yet approved for pain indications.
Authors
- Skaorat Panchoowong (ORCID: https://orcid.org/0000-0002-8152-7343)
- Mark P. Jensen (ORCID: https://orcid.org/0000-0003-3392-9767)
- Wanna Srirojanakul
- Nattha Saisavoey (ORCID: https://orcid.org/0000-0001-6278-3440)
- Suratsawadee Wangnamthip (ORCID: https://orcid.org/0000-0002-6795-8550)
- Thanompong Sathienluckana (ORCID: https://orcid.org/0000-0002-0330-8954)
- Pramote Euasobhon (ORCID: https://orcid.org/0000-0001-5268-5476)
- Isaraporn Tipapakoon
- Sarasate Eiamtanasate
- Lucksika Suthisiltham
Institutions
- Siam University (TH)
- Siriraj Hospital (TH)
- University of Washington (US)
- Mahidol University (TH)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jpr.s568131
- Primary Topic
- Musculoskeletal pain and rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University
- Faculty of Medicine Siriraj Hospital, Mahidol University