LRG1 Drives AML Progression by Disrupting Myeloid Progenitor Regulation
Our findings establish LRG1 as a robust prognostic biomarker and a key functional regulator of AML maintenance through myeloid progenitor dysregulation, presenting it as a promising target for new therapeutic strategies.
Authors
- Rongxia Guo
- Fumei Liu (ORCID: https://orcid.org/0000-0002-7614-6693)
- Peng Wu
- Shuxin Yao (ORCID: https://orcid.org/0009-0001-1444-2569)
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- Blood and Lymphatic Cancer Targets and Therapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/blctt.s556618
- Primary Topic
- Clusterin in disease pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00