Leveraging the baculovirus-insect cell expression system for optimal AAV scale-up

David McCall, Senior Editor, BioInsights, speaks to VectorY Therapeutics’ Barbara Sanders, Co-founder and CTO, and Femke Hoeksema, Director of Process Development, about their innovative work on gene therapies for neurodegenerative diseases, including vectorized antibody treatments for amyotrophic lateral sclerosis. They also discuss the considerations and advantages in utilizing a baculovirus-based AAV production system versus other upstream viral vector production platforms.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2024-09-19
DOI
https://doi.org/10.18609/cgti.2024.129
Primary Topic
Viral Infectious Diseases and Gene Expression in Insects
Type
article
Field-Weighted Citation Impact
0.00
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article

Leveraging the baculovirus-insect cell expression system for optimal AAV scale-up

Barbara P. Sanders, Femke Hoeksema
Cell and Gene Therapy Insights
Viral Infectious Diseases and Gene Expression in Insects
article

Leveraging the baculovirus-insect cell expression system for optimal AAV scale-up

Barbara P. Sanders, Femke Hoeksema
article en

Abstract

David McCall, Senior Editor, BioInsights, speaks to VectorY Therapeutics’ Barbara Sanders, Co-founder and CTO, and Femke Hoeksema, Director of Process Development, about their innovative work on gene therapies for neurodegenerative diseases, including vectorized antibody treatments for amyotrophic lateral sclerosis. They also discuss the considerations and advantages in utilizing a baculovirus-based AAV production system versus other upstream viral vector production platforms.

Cell and Gene Therapy InsightsVol. 10(8)
AIMM Therapeutics (Netherlands) (NL)
Openalex Percentile: Top 76%
Viral Infectious Diseases and Gene Expression in Insects
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