Supporting efficacy and scaling with a next-generation T cell AOF formulation medium
Cell culture media are critical to successful cell therapy production, serving as a source of essential nutrients and maintaining the physiological conditions necessary for optimal cell growth and function. The use of well-defined, animal origin-free (AOF) media is increasingly recognized as being pivotal in ensuring experimental reproducibility, minimizing contamination risks, and addressing stringent regulatory requirements. This article explores the CTS™ OpTmizer™ One serum-free medium, an innovative AOF formulation tailored for T cell expansion. This medium is designed to enhance the early memory T cell phenotype, improve cell viability, and facilitate scalability, positioning it as a crucial tool for both preclinical research and clinical manufacturing.
Authors
- Arie Lang Gutowski
- J. Kern (ORCID: https://orcid.org/0000-0001-5019-4104)
Institutions
- Thermo Fisher Scientific (United States) (US)
Publication Details
- Journal
- Cell and Gene Therapy Insights
- Published
- 2024-10-01
- DOI
- https://doi.org/10.18609/cgti.2024.138
- Primary Topic
- Viral Infectious Diseases and Gene Expression in Insects
- Type
- article
- Field-Weighted Citation Impact
- 0.00