Accelerating AAV process development with a PAT-driven TFF system

Ultrafiltration/diafiltration (UF/DF) represents a crucial step in bioprocessing, but traditional methods can pose a range of challenges. This poster describes streamlined process development with a system uniquely controlled by real-time titer measurement acquired through in-line variable pathlength spectroscopy.AAV case study data demonstrates automated process control, exhibiting the system’s efficacy across various final endpoints.

Authors

Publication Details

Journal
Cell and Gene Therapy Insights
Published
2024-10-31
DOI
https://doi.org/10.18609/cgti.2024.148
Primary Topic
Membrane Separation Technologies
Type
article
Field-Weighted Citation Impact
0.00
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article

Accelerating AAV process development with a PAT-driven TFF system

Teva Smith
Cell and Gene Therapy Insights
Membrane Separation Technologies
article

Accelerating AAV process development with a PAT-driven TFF system

Teva Smith
article en

Abstract

Ultrafiltration/diafiltration (UF/DF) represents a crucial step in bioprocessing, but traditional methods can pose a range of challenges. This poster describes streamlined process development with a system uniquely controlled by real-time titer measurement acquired through in-line variable pathlength spectroscopy.AAV case study data demonstrates automated process control, exhibiting the system’s efficacy across various final endpoints.

Cell and Gene Therapy InsightsVol. 10(9)
Openalex Percentile: Top 71%
Membrane Separation Technologies
DOISourceOpenAlex
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Accelerating AAV process development with a PAT-driven TFF system — Teva Smith · Cell and Gene Therapy Insights (2024) | TGRS Research Map | TGRS