Autologous platelet rich fibrin with or without bovine porous bone (Bio-Oss) in socket preservation

Abstract Background The changes in alveolar dimension after tooth extraction may greatly alter treatment decisions including the ability to place a dental implant for optimal esthetics and long-term success. Maintaining an adequate alveolar ridge volume is essential for successful implant. Objectives The aim of the present study was to evaluate and compare clinically and radiographically by cone beam computed tomography the effectiveness of autologous platelet-rich fibrin (PRF) with or without bovine porous (Bio-Oss) in socket preservation. Patients and methods A total of 21 hopeless teeth indicated for extraction due to factors other than severe periodontal diseases were selected and divided into three groups. Group I: the extracted sockets left without filling materials and considered as control, versus group II: the extracted sockets filled by autologous PRF only and group III: the extracted sockets filled with mixture of PRF and Bio-Oss in class I extracted socket. Results Soft tissue healing results: The three groups showed improvement regarding to the soft tissue healing. The soft tissue healing was better in group II (PRF only) then group III (Bio-Oss + PRF) then group I (without filling) was the least. Radiographic results: At baseline, statistical analysis of data revealed no significant differences between the measurements of the radiographic parameters, socket length, and bone density. Comparing between the three groups after 6 months regarding to socket length, group I and II, group I and III and group II and III there were no statistically significant differences. Comparing between the three groups after 6 months regarding to (bone density) group I and II, there was statistically significant difference values in favor of group II, between GI and GIII there was statistically significant difference values, in favor to group III and between GII and GIII there was statistically significant difference in favor to group III. Conclusions PRF used in the extraction sockets promote local soft tissue healing of the socket and reduce postoperative pain response. It could not be concluded that PRF alone or mixture of (PRF + Bio-Oss) used as socket augmentation were effective in reducing alveolar bone resorption in the vertical/apex-coronal dimension. PRF and mixture of PRF + Bio-Oss able to increase the quality and density of bone which is essential for the success of osseointegration of the implant.