Risk factors analysis for pathological upgrade after endoscopic submucosal dissection in patients with gastric intraepithelial neoplasia: a single-center retrospective study

Advanced age (⩾70 years), hypertension, lesion size ⩾2 cm, type IIc morphology, and lesions in the gastric angle/cardia significantly increase the risk of pathological upgrade after ESD. These findings provide a basis for preoperative risk assessment and individualized treatment strategies for GIN patients.

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Journal
Therapeutic Advances in Gastroenterology
Published
2025-12-01
DOI
https://doi.org/10.1177/17562848251397847
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
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article

Risk factors analysis for pathological upgrade after endoscopic submucosal dissection in patients with gastric intraepithelial neoplasia: a single-center retrospective study

Jia-Le Lv, Ke Chen, Lijia Ding, Qiang Zhan et al.
Therapeutic Advances in Gastroenterology
Gastric Cancer Management and Outcomes
article

Risk factors analysis for pathological upgrade after endoscopic submucosal dissection in patients with gastric intraepithelial neoplasia: a single-center retrospective study

Jia-Le Lv, Ke Chen, Lijia Ding, Qiang Zhan, He Nie, Shuping Si, Fangmei An, Ji Lin, Yunan Zhang, Zhifa Lv, Wenying Tian, Rong Liu, Juntao Li, Qinglin Zhang, Xiaoxue Zhang, Fengjun Sun, J. Han
article en

Abstract

Advanced age (⩾70 years), hypertension, lesion size ⩾2 cm, type IIc morphology, and lesions in the gastric angle/cardia significantly increase the risk of pathological upgrade after ESD. These findings provide a basis for preoperative risk assessment and individualized treatment strategies for GIN patients.

Therapeutic Advances in GastroenterologyVol. 18
Scientific Services (ZA), Wuxi People's Hospital (CN)
Openalex Percentile: Top 41%
Gastric Cancer Management and Outcomes
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Risk factors analysis for pathological upgrade after endoscopic submucosal dissection in patients with gastric intraepithelial neoplasia: a single-center retrospective study — Jia-Le Lv, Ke Chen, et al. · Therapeutic Advances in Gastroenterology (2025) | TGRS Research Map | TGRS