Exploitation of Biocomputational Approaches for <scp>siRNA</scp> ‐Mediated Gene Silencing of <scp>HPV</scp> : A Novel Therapeutic Strategy for Cervical Cancer

The study revealed the potential of the designed siRNAs in silencing the E6 and E7 genes and their therapeutic applications against HPV. Future research should focus on validating these findings across various experiments, both in vivo and in vitro, and exploring alternative delivery approaches to enhance therapeutic efficacy.

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Publication Details

Journal
Cancer Reports
Published
2025-12-01
DOI
https://doi.org/10.1002/cnr2.70434
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploitation of Biocomputational Approaches for siRNA ‐Mediated Gene Silencing of HPV : A Novel Therapeutic Strategy for Cervical Cancer

Aklima Akter, Md. Habib Ullah Masum, Jannatul Ferdous, Rehana Parvin et al.
Cancer Reports
RNA Interference and Gene Delivery
article

Exploitation of Biocomputational Approaches for siRNA ‐Mediated Gene Silencing of HPV : A Novel Therapeutic Strategy for Cervical Cancer

Aklima Akter, Md. Habib Ullah Masum, Jannatul Ferdous, Rehana Parvin, Homaira Pervin Heema
article en

Abstract

The study revealed the potential of the designed siRNAs in silencing the E6 and E7 genes and their therapeutic applications against HPV. Future research should focus on validating these findings across various experiments, both in vivo and in vitro, and exploring alternative delivery approaches to enhance therapeutic efficacy.

Cancer ReportsVol. 8(12)
Chittagong Medical College (BD), Institut thématique Génétique, génomique et bioinformatique (FR), Chattogram Veterinary and Animal Sciences University (BD)
Openalex Percentile: Top 63%
RNA Interference and Gene Delivery
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