Inflammation in Diabetic Kidney Disease Is Linked to Gut Dysbiosis and Metabolite Imbalance
Gut barrier dysfunction and gut microbiota imbalance may mediate the pro-inflammatory immune phenotype observed in patients with DKD and thereby contribute to DKD progression. These findings underscore the important role of the microbiota-immune axis in the development of DKD.
Authors
- Jiali Wang (ORCID: https://orcid.org/0009-0009-8131-6122)
- Xilian Wang (ORCID: https://orcid.org/0000-0001-7336-1120)
- Xiaoan Li (ORCID: https://orcid.org/0009-0006-8293-8845)
- Xiaoyan Luo
- Xueting Zheng
- Huan Liu (ORCID: https://orcid.org/0009-0003-5399-1928)
- Yi Zhang (ORCID: https://orcid.org/0000-0001-8373-017X)
- Lu Zhou (ORCID: https://orcid.org/0000-0002-7689-0033)
- Junyi Yang (ORCID: https://orcid.org/0000-0001-9190-1522)
- Zhiyan Zou (ORCID: https://orcid.org/0000-0002-7225-9092)
- Fangfang Cao (ORCID: https://orcid.org/0000-0002-0520-8287)
- Xiangting Ge (ORCID: https://orcid.org/0000-0001-9184-7079)
Institutions
- North Sichuan Medical University (CN)
- Southwest University of Science and Technology (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Mianyang Central Hospital (CN)
Publication Details
- Journal
- Journal of Diabetes
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/1753-0407.70175
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Sichuan Province