Neutrophil-to-lymphocyte ratio: a potential supportive marker for elderly community-acquired bloodstream infections—a retrospective study

The increase in NLR was superior to the rise of traditional white blood cell and neutrophil counts. Thus, NLR can be used as an indication for the early diagnosis of community-acquired bloodstream infection in the elderly. The optimal cutoff value of NLR for supporting the diagnosis of community-acquired bloodstream infections in elderly patients was determined to be 8.0. When NLR exceeds this threshold (> 8.0), it serves as a clinical alert for community physicians, indicating a significantly elevated probability of elderly patients developing community-acquired bloodstream infections.

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Publication Details

Journal
PeerJ
Published
2025-12-08
DOI
https://doi.org/10.7717/peerj.20449
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Neutrophil-to-lymphocyte ratio: a potential supportive marker for elderly community-acquired bloodstream infections—a retrospective study

J. Zhang, Peijuan Li, Qianqian Pei, Kun Chen et al.
PeerJ
Neonatal and Maternal Infections
article

Neutrophil-to-lymphocyte ratio: a potential supportive marker for elderly community-acquired bloodstream infections—a retrospective study

J. Zhang, Peijuan Li, Qianqian Pei, Kun Chen, Chunmei Wang, Mengxi Ding
article en

Abstract

The increase in NLR was superior to the rise of traditional white blood cell and neutrophil counts. Thus, NLR can be used as an indication for the early diagnosis of community-acquired bloodstream infection in the elderly. The optimal cutoff value of NLR for supporting the diagnosis of community-acquired bloodstream infections in elderly patients was determined to be 8.0. When NLR exceeds this threshold (> 8.0), it serves as a clinical alert for community physicians, indicating a significantly elevated probability of elderly patients developing community-acquired bloodstream infections.

PeerJVol. 13
Capital Medical University (CN), West China Medical Center of Sichuan University (CN), Jianghan University (CN), Beijing Aerospace General Hospital (CN)
Openalex Percentile: Top 49%
Neonatal and Maternal Infections
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Neutrophil-to-lymphocyte ratio: a potential supportive marker for elderly community-acquired bloodstream infections—a retrospective study — J. Zhang, Peijuan Li, et al. · PeerJ (2025) | TGRS Research Map | TGRS