Tablet‐based Cognitive Assessment Tool (TabCAT) in a multisite study of early‐onset Alzheimer's disease
Four hundred seventy-five participants from 16 US sites underwent tablet-based cognitive assessment. Digital tests assessed executive function and visuospatial abilities. Digital tests correlated with traditional pen-and-paper cognitive tests. Match (test of executive function) differentiated clinical groups. Digital tests were associated with amyloid positron emission tomography (PET) status and regional tau PET patterns.
Authors
- Konstantinos Chiotis (ORCID: https://orcid.org/0000-0002-5679-0297)
- J. Zhang (ORCID: https://orcid.org/0000-0003-2572-2555)
- Alexandra Touroutoglou (ORCID: https://orcid.org/0000-0001-9679-2433)
- Michael Brickhouse
- Lawrence S. Honig (ORCID: https://orcid.org/0000-0002-9703-2265)
- Clifford R. Jack (ORCID: https://orcid.org/0000-0001-7916-622X)
- Alireza Atri (ORCID: https://orcid.org/0000-0003-4405-6973)
- Ranjani P. Shankar (ORCID: https://orcid.org/0009-0002-1726-9690)
- Piyush Maiti (ORCID: https://orcid.org/0009-0002-8006-1032)
- Renaud La Joie (ORCID: https://orcid.org/0000-0003-2581-8100)
- Alexander Taurone
- Joel H. Kramer (ORCID: https://orcid.org/0000-0002-2917-8297)
- Joseph C. Masdeu (ORCID: https://orcid.org/0000-0001-9955-6954)
- Erik S. Musiek (ORCID: https://orcid.org/0000-0002-8873-0360)
- Ian Grant (ORCID: https://orcid.org/0000-0001-6960-6762)
- Liana G. Apostolova (ORCID: https://orcid.org/0000-0003-1823-2451)
- Paul S. S Aisen (ORCID: https://orcid.org/0000-0002-2896-5838)
- David A. Wolk (ORCID: https://orcid.org/0000-0002-3554-3481)
- Erik C. B. Johnson (ORCID: https://orcid.org/0000-0002-0604-2944)
- Prashanthi Vemuri (ORCID: https://orcid.org/0000-0003-4286-0589)
- Chiadi U. Onyike (ORCID: https://orcid.org/0000-0003-2255-4437)
- Elena Tsoy (ORCID: https://orcid.org/0000-0001-8786-1791)
- Robert Koeppe
- Gil Dan Rabinovici (ORCID: https://orcid.org/0000-0002-3626-4265)
- Dustin B. Hammers (ORCID: https://orcid.org/0000-0002-1644-2618)
- Kyle Womack (ORCID: https://orcid.org/0000-0002-6060-9075)
- Sandra Rocha (ORCID: https://orcid.org/0000-0002-4530-3537)
- Laurel Beckett (ORCID: https://orcid.org/0000-0002-2418-9843)
- Sharon J. Sha (ORCID: https://orcid.org/0000-0002-3666-1463)
- Emily Rogalskı (ORCID: https://orcid.org/0000-0002-6472-1363)
- Isabel Elaine Allen (ORCID: https://orcid.org/0000-0001-9029-9744)
- Walter A. Kukull (ORCID: https://orcid.org/0000-0001-8761-9014)
- Gregory Scott Day (ORCID: https://orcid.org/0000-0001-5133-5538)
- David Thomas Jones (ORCID: https://orcid.org/0000-0002-4807-9833)
- Kelly Nudelman (ORCID: https://orcid.org/0000-0003-4040-1717)
- Ganna Blazhenets (ORCID: https://orcid.org/0000-0003-2419-7373)
- David A. Clark (ORCID: https://orcid.org/0000-0002-8334-492X)
- Wepnyu Yembe Njamnshi (ORCID: https://orcid.org/0000-0001-5082-7960)
- Marcus A. Lawson
- Mario F. Mendez (ORCID: https://orcid.org/0000-0001-6441-7989)
- Ani Eloyan (ORCID: https://orcid.org/0000-0002-8110-7680)
- Katherine L. Possin (ORCID: https://orcid.org/0000-0002-6623-3793)
- Ranjan Duara (ORCID: https://orcid.org/0000-0001-8060-6309)
- Bradford Clark Dickerson (ORCID: https://orcid.org/0000-0002-5958-3445)
- Raymond Scott Turner (ORCID: https://orcid.org/0000-0001-7534-2935)
- Alinda Amuiri
- Thomas S. Wingo (ORCID: https://orcid.org/0000-0002-7679-6282)
- Marı́a C. Carrillo
- Arthur W. Toga
- Neill R. Graff‐Radford
- Kala Kirby
- Steven Salloway
- Maryanne Thangarajah
- Meghan Riddle
Institutions
- Northwestern University (US)
- University of Southern California (US)
- Alzheimer's Association (US)
- Autism Research Institute (US)
- Houston Methodist (US)
- Rhode Island Department of Health (US)
- Mayo Clinic (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Emory University (US)
- University of California, Los Angeles (US)
- University of California, San Francisco (US)
- Georgetown University (US)
- University of Washington (US)
- Washington University in St. Louis (US)
- Cornell University (US)
- Brown University (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Johns Hopkins Medicine (US)
- Jacksonville College (US)
- University of California System (US)
- University of Chicago (US)
- Massachusetts General Hospital (US)
- Mount Sinai Medical Center (US)
- University Memory and Aging Center (US)
- Methodist Hospital (US)
- Ministry of Public Health (CM)
- Banner Sun Health Research Institute (US)
- Mayo Clinic in Florida (US)
- Global Brain Health Institute (US)
- University of Lomé (TG)
- Weill Cornell Medicine (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- Stanford University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz.71012
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- Avid Radiopharmaceuticals
- National Institute on Aging