Antifibrotic and anti-inflammatory properties of halofuginone in a rat craniectomy model

These findings indicate that halofuginone effectively reduces fibrotic tissue formation at craniectomy sites, potentially by suppressing collagen synthesis and inflammatory responses. Further studies are warranted to explore its clinical applications in preventing postoperative fibrosis.

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Publication Details

Journal
Ulusal travma dergisi
Published
2025-01-01
DOI
https://doi.org/10.14744/tjtes.2025.70707
Primary Topic
Quinazolinone synthesis and applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Antifibrotic and anti-inflammatory properties of halofuginone in a rat craniectomy model

Tuncer Taşçıoğlu
Ulusal travma dergisi
Quinazolinone synthesis and applications
article

Antifibrotic and anti-inflammatory properties of halofuginone in a rat craniectomy model

Tuncer Taşçıoğlu
article en

Abstract

These findings indicate that halofuginone effectively reduces fibrotic tissue formation at craniectomy sites, potentially by suppressing collagen synthesis and inflammatory responses. Further studies are warranted to explore its clinical applications in preventing postoperative fibrosis.

Ulusal travma dergisiVol. 31(11)
Ministry of Health (TR), University of Health Science (KH), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Openalex Percentile: Top 70%
Quinazolinone synthesis and applications
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