Chemical composition of the roots of <i>Angelica acutiloba n</i> -butanol extracts and their anti-inflammatory activities

A phytochemical examination of the roots of <i>Angelica acutiloba</i> was undertaken, resulting in the identification of 21 distinct constituents. NMR spectroscopic characterisation revealed the presence of flavonoids, lignans, monoterpenes, aldehydes, amino acids, alkaloids, benzofurans, phenylpropanoids, glycosides, and sac-charides. Among these, two monoterpenes and one lignan were identified as previously undescribed compounds, designated as <b>Angeliterpene A</b> (<b>1</b>), <b>Angeliterpene B</b> (<b>2</b>) and <b>Angelignan A</b> (<b>3</b>), respectively. Furthermore, the results indicated that novel compounds <b>1</b>, <b>2</b>, <b>3</b>, as well as compounds <b>6</b>, <b>7</b>, and <b>13</b>, exhibited nitric oxide (NO) inhibitory activity, with compound <b>6</b> demonstrating the most potent effect.