Role and mechanism of the CBX4-HDAC5-CERS6 axis in disrupting sphingomyelin metabolism in acute myeloid leukemia
The CBX4-HDAC5-CERS6 axis influences AML malignant progression by regulating sphingolipid metabolism, and targeted intervention of this axis may represent a novel therapeutic strategy for AML.
Authors
- Ruifang Ye (ORCID: https://orcid.org/0000-0002-2729-9116)
Institutions
- Guangdong Medical College (CN)
- Dongguan People’s Hospital (CN)
Publication Details
- Journal
- American Journal of Cancer Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62347/vxbp2060
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00