Agentic artificial intelligence in cognitive screening: A translational roadmap for dementia care

Conventional dementia screening tools, whether paper tests or static artificial intelligence (AI) models, capture only a snapshot of cognition and need to be adminstered periodically. Yet decline is dynamic, shaped by environment, comorbidities, and life history. Current approaches rarely adapt, integrate feedback, or provide transparent reasoning that clinicians can trust. We propose agentic AI systems: modular agents built on large language models (LLMs) that collaborate, adapt, and mirror interdisciplinary care. The Cognitive Agent Lab exemplifies this framework, emphasizing functional aspects (inputs, outputs, workflows) and non-functional aspects (transparency, adaptivity, robustness, clinical alignment). Embedding reasoning and collaboration, agentic AI offers a roadmap toward more personalized and explainable cognitive health tools.

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Publication Details

Journal
Journal of Alzheimer s Disease Reports
Published
2025-01-01
DOI
https://doi.org/10.1177/25424823251407989
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

Agentic artificial intelligence in cognitive screening: A translational roadmap for dementia care

Faisal Aqlan, Hui Yang, Kevin Mekulu
Journal of Alzheimer s Disease Reports
Artificial Intelligence in Healthcare and Education
article

Agentic artificial intelligence in cognitive screening: A translational roadmap for dementia care

Faisal Aqlan, Hui Yang, Kevin Mekulu
article en

Abstract

Conventional dementia screening tools, whether paper tests or static artificial intelligence (AI) models, capture only a snapshot of cognition and need to be adminstered periodically. Yet decline is dynamic, shaped by environment, comorbidities, and life history. Current approaches rarely adapt, integrate feedback, or provide transparent reasoning that clinicians can trust. We propose agentic AI systems: modular agents built on large language models (LLMs) that collaborate, adapt, and mirror interdisciplinary care. The Cognitive Agent Lab exemplifies this framework, emphasizing functional aspects (inputs, outputs, workflows) and non-functional aspects (transparency, adaptivity, robustness, clinical alignment). Embedding reasoning and collaboration, agentic AI offers a roadmap toward more personalized and explainable cognitive health tools.

Journal of Alzheimer s Disease ReportsVol. 9
Pennsylvania State University (US), University of Louisville (US), University of Louisville Hospital (US)
Openalex Percentile: Top 65%
Artificial Intelligence in Healthcare and Education
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