Surgical excision versus topical 5% 5-fluorouracil and photodynamic therapy in the treatment of Bowen's disease: Long-term results of a multicenter randomized controlled trial
During long-term follow-up, the additional risk of recurrence of BD after 5FU and SE, and the risk of developing a cSCC from a treated BD were negligible. Treatment with 5FU remains non-inferior to SE, whereas non-inferiority of MAL-PDT could not be concluded.
Authors
- J.P.H.M. Kessels (ORCID: https://orcid.org/0000-0002-1213-5469)
- Nicole W.J. Kelleners-Smeets (ORCID: https://orcid.org/0000-0001-6542-7740)
- Klara Mosterd (ORCID: https://orcid.org/0000-0002-9065-3050)
- Shima Ahmady (ORCID: https://orcid.org/0000-0002-9551-1721)
- Myrthe M G Moermans (ORCID: https://orcid.org/0009-0003-9236-0379)
- A.H.M.M. Arits
- Han P.A. van Pelt
- Patty J. Nelemans
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- Maastricht University (NL)
- VieCuri Medisch Centrum (NL)
- Zuyderland Medisch Centrum (NL)
Publication Details
- Journal
- Journal of the American Academy of Dermatology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jaad.2025.12.034
- Primary Topic
- Nonmelanoma Skin Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00