Characterization of Nanocapsules of Sodium Alginate and Moringa oleifera Extract by AFM as a Therapeutic Alternative

Alginate nanocapsules loaded with <i>Moringa oleifera</i> extract, a plant traditionally used for its hypoglycemic properties, were developed as a therapeutic alternative for type II diabetes mellitus. The nanocapsules were obtained by manually spraying a WO emulsion with an airbrush and were stabilized in 2% calcium chloride. Characterization by atomic force microscopy revealed spherical particles with an average diameter of 10.087 nm, an area of 298.441 nm<sup>2</sup>, and a density of 0.207556/nm<sup>2</sup>, confirming efficient encapsulation and uniform morphology. This low-cost method is promising for the creation of controlled release systems in resource-limited settings.

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Published
2025-12-11
DOI
https://doi.org/10.3390/materproc2025028002
Primary Topic
Moringa oleifera research and applications
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article
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article

Characterization of Nanocapsules of Sodium Alginate and Moringa oleifera Extract by AFM as a Therapeutic Alternative

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Moringa oleifera research and applications
article

Characterization of Nanocapsules of Sodium Alginate and Moringa oleifera Extract by AFM as a Therapeutic Alternative

Francisco Emanuel Velásquez Hernández, Fernando Mejía Zarate, Arturo Zapién Martínez, E. Marroquin, Antonio Canseco Urbieta, Ivonne Arisbeth Díaz Santiago
article en

Abstract

Alginate nanocapsules loaded with <i>Moringa oleifera</i> extract, a plant traditionally used for its hypoglycemic properties, were developed as a therapeutic alternative for type II diabetes mellitus. The nanocapsules were obtained by manually spraying a WO emulsion with an airbrush and were stabilized in 2% calcium chloride. Characterization by atomic force microscopy revealed spherical particles with an average diameter of 10.087 nm, an area of 298.441 nm<sup>2</sup>, and a density of 0.207556/nm<sup>2</sup>, confirming efficient encapsulation and uniform morphology. This low-cost method is promising for the creation of controlled release systems in resource-limited settings.

Benito Juárez Autonomous University of Oaxaca (MX)
Openalex Percentile: Top 71%
Moringa oleifera research and applications
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