A systematic review of outcomes following transhumeral amputation for brachial plexus injury

Transhumeral amputation following brachial plexus injury yields clinically meaningful functional gains and high patient satisfaction, especially when combined with modern prosthetic technology. Pain reduction is variable, and return-to-work rates remain modest. Amputation should be considered a valid reconstructive endpoint in selected patients when conventional nerve reconstruction fails. Future multicentre prospective studies employing standardised outcome measures are essential to refine patient selection, quantify long-term benefit, and optimise multidisciplinary rehabilitation strategies.