Aggressive Juvenile-Onset Respiratory Papillomatosis in a High HIV Prevalence Setting: Clinical Predictors of Severity in South Africa
Early age at diagnosis and exposure to maternal HIV are potential predictors of aggressive JoRRP in high HIV-prevalence settings. These findings underscore the importance of integrated maternal-child healthcare, and robust public health interventions, such as expanded HPV vaccination and enhanced HIV prevention strategies, to reduce the clinical burden of JoRRP.
Authors
- Elisa Evangelista (ORCID: https://orcid.org/0009-0006-0852-9066)
- Madison Tyle
- Suriamurthee Moonsamy Maistry
- Andile Lindokuhle Sibiya (ORCID: https://orcid.org/0000-0002-9787-821X)
- Yijian Liang (ORCID: https://orcid.org/0000-0003-4957-6919)
- J. Zachary Porterfield (ORCID: https://orcid.org/0000-0002-2724-9928)
- Tashlen Abel (ORCID: https://orcid.org/0000-0002-7808-6161)
- Nokukhanya Msomi (ORCID: https://orcid.org/0000-0002-0610-6100)
- Riaz Y. Seedat (ORCID: https://orcid.org/0000-0002-9774-334X)
- Yougan Saman
Institutions
- National Health Laboratory Service (ZA)
- University of South Florida (US)
- University of the Free State (ZA)
- St. Mary’s Hospital (ZA)
- Imperial College London (GB)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1093/ofid/ofaf741
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00