Antibodies to combat melioidosis: bridging immune mechanisms with diagnostics and therapeutic potential

Antibody responses to key virulence factors correlate with disease course and are increasingly studied for diagnostic and therapeutic applications. This review aids in informing novel diagnostics and guide antibody-based therapies offering new directions for clinical management and prevention of this high-burden but underrecognized infection.

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Publication Details

Journal
Current Opinion in Infectious Diseases
Published
2025-12-01
DOI
https://doi.org/10.1097/qco.0000000000001174
Primary Topic
Burkholderia infections and melioidosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Antibodies to combat melioidosis: bridging immune mechanisms with diagnostics and therapeutic potential

W. Joost Wiersinga, Emma Birnie, Partha Paul, Roos I. Frölke
Current Opinion in Infectious Diseases
Burkholderia infections and melioidosis
article

Antibodies to combat melioidosis: bridging immune mechanisms with diagnostics and therapeutic potential

W. Joost Wiersinga, Emma Birnie, Partha Paul, Roos I. Frölke
article en

Abstract

Antibody responses to key virulence factors correlate with disease course and are increasingly studied for diagnostic and therapeutic applications. This review aids in informing novel diagnostics and guide antibody-based therapies offering new directions for clinical management and prevention of this high-burden but underrecognized infection.

Current Opinion in Infectious DiseasesVol. 39(2)
Netherlands Center for Occupational Diseases (NL), Amsterdam Neuroscience (NL), Office of Infectious Diseases (US), Institute of Infection and Immunity (CA)
Openalex Percentile: Top 48%
Burkholderia infections and melioidosis
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