Safety of Vedolizumab in Pregnancy

Vedolizumab exposure during pregnancy in individuals with IBD was not associated with increased odds of early pregnancy loss, congenital malformations, or composite perinatal complications. However, increased odds of preterm birth and cesarean delivery were observed, potentially reflecting underlying disease severity.

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Publication Details

Journal
Journal of Clinical Gastroenterology
Published
2025-12-05
DOI
https://doi.org/10.1097/mcg.0000000000002310
Primary Topic
Pregnancy and Medication Impact
Type
article
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article

Safety of Vedolizumab in Pregnancy

Astrid‐Jane Williams, Bachviet Nguyen, Yvette Leung, Stephanie Quon
Journal of Clinical Gastroenterology
Pregnancy and Medication Impact
article

Safety of Vedolizumab in Pregnancy

Astrid‐Jane Williams, Bachviet Nguyen, Yvette Leung, Stephanie Quon
article en

Abstract

Vedolizumab exposure during pregnancy in individuals with IBD was not associated with increased odds of early pregnancy loss, congenital malformations, or composite perinatal complications. However, increased odds of preterm birth and cesarean delivery were observed, potentially reflecting underlying disease severity.

Journal of Clinical GastroenterologyVol. 60(3)
University of British Columbia (CA), Vancouver Infectious Diseases Centre (CA)
Openalex Percentile: Top 49%
Pregnancy and Medication Impact
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