Treatment Outcome and Chemoresistance-Related Factors of Low-Risk Gestational Trophoblastic Neoplasia: Results From a Tertiary Care Center in Saudi Arabia

Patients with FIGO scores of 5-6 and high β-hCG levels had increased resistance to first-line therapy. β-hCG was the strongest independent predictor. These findings highlight the need to reassess treatment strategies for this subgroup.

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Publication Details

Journal
JCO Global Oncology
Published
2025-12-01
DOI
https://doi.org/10.1200/go-25-00172
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
Field-Weighted Citation Impact
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article

Treatment Outcome and Chemoresistance-Related Factors of Low-Risk Gestational Trophoblastic Neoplasia: Results From a Tertiary Care Center in Saudi Arabia

Abdulrahman Alghabban, Mohamed Aseafan, Alanoud Alhumaidi, Shouki Bazarbashi et al.
JCO Global Oncology
Gestational Trophoblastic Disease Studies
article

Treatment Outcome and Chemoresistance-Related Factors of Low-Risk Gestational Trophoblastic Neoplasia: Results From a Tertiary Care Center in Saudi Arabia

Abdulrahman Alghabban, Mohamed Aseafan, Alanoud Alhumaidi, Shouki Bazarbashi, Nermin Fahmy, Irfan Maghfoor, Ahmed Gad, Rahaf Ahmed Ali Alshihri, Inaam Ahmed Ibrahim, Hamed Alhusseini, Bader Alshamsan, Zainab Aziz Al-Sahwan
article en

Abstract

Patients with FIGO scores of 5-6 and high β-hCG levels had increased resistance to first-line therapy. β-hCG was the strongest independent predictor. These findings highlight the need to reassess treatment strategies for this subgroup.

JCO Global OncologyVol. 11(11)
Ain Shams University (EG), Suez Canal University (EG), Alfaisal University (SA), Qassim University (SA), King Faisal Specialist Hospital & Research Centre (SA), Security Forces Hospital (SA)
Openalex Percentile: Top 49%
Gestational Trophoblastic Disease Studies
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