A Clinical Trial to Evaluate the Laxative Effect of Panchasakara Choorna in the Management of Vibandha with Special Reference to Constipation

Introduction:Constipation is a prevalent gastrointestinal complaint in the community. It is a major feature of disorders of colorectal motility and has a varying prevalence. Vibandha mentioned in Ayurveda can be clinically correlated with constipation. Panchasakara Choorna is a compound formulation indicated for the management of Vibandha. Objective:The objective of this study was to evaluate the effect of Panchasakara Choorna in the management of Vibandha. Methods:The study was an open-label, single-arm, interventional trial. A total of 30 subjects were recruited based on the assessment criteria, and a test drug was administered for 2 weeks. Assessment was done at an interval of day 0, day 7, day 14, and day 21. Results:Study results showed a significant decline in straining during defecation, sense of incomplete evacuation, sense of anorectal blockage, and lumpy hard stools. Posttreatment follow-up on day 21 showed no significant relapse of the symptoms of Vibandha. Conclusion:Oral administration of 3 g of Panchasakara Choorna once daily at bedtime for 2 weeks of duration showed a highly significant effect in pacifying the symptoms of Vibandha.