Dual Treponemal and Non-Treponemal Rapid Test for Syphilis in People Living with HIV: A Diagnostic Accuracy Study
In PLHIV, the serum-based DPP-SSCA did not meet WHO performance targets. Given the low specificity of the non-treponemal component, the development of improved diagnostic tools and rigorous validation are needed to ensure reliable and rapid diagnosis of active syphilis infection in this population.
Authors
- Arlene C. Seña (ORCID: https://orcid.org/0000-0002-1206-2175)
- José Fernando Fuertes-Bucheli (ORCID: https://orcid.org/0000-0002-3810-4943)
- Jonny Alejandro García Luna (ORCID: https://orcid.org/0000-0002-4784-6519)
- Sebastian Alejandro Silva Peña (ORCID: https://orcid.org/0000-0002-1637-7510)
- Lady G. Ramírez (ORCID: https://orcid.org/0000-0003-0423-857X)
- Kelly L. Hawley (ORCID: https://orcid.org/0000-0001-8587-1662)
- Álvaro Martínez (ORCID: https://orcid.org/0000-0002-5641-2392)
- Luisa Hurtado-Rossi (ORCID: https://orcid.org/0000-0001-9411-0785)
- Carol Ospina-Cortes (ORCID: https://orcid.org/0009-0001-9029-9565)
Institutions
- University of North Carolina at Chapel Hill (US)
- Children’s Institute (US)
- Centro Internacional de Entrenamiento e Investigaciones Medicas (CO)
- Fundación Valle del Lili (CO)
- Connecticut Children's Medical Center (US)
- UConn Health (US)
- Icesi University (CO)
Publication Details
- Journal
- Sexually Transmitted Diseases
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1097/olq.0000000000002278
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00