Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability

In this wide-ranging interview David McCall, Senior Editor, BioInsights, and Ben Andrews, Senior Manager in Strategic External Development, GlaxoSmithKline, discuss the key challenges and opportunities for successful oligonucleotide manufacturing at scale, the merits and drawbacks of various synthesis options, and current efforts to mitigate the industry’s environmental impact.

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Publication Details

Journal
Nucleic Acid Insights
Published
2024-11-26
DOI
https://doi.org/10.18609/nai.2024.041
Primary Topic
Chemistry and Chemical Engineering
Type
article
Field-Weighted Citation Impact
0.00
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article

Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability

B. J. Andrews
Nucleic Acid Insights
Chemistry and Chemical Engineering
article

Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability

B. J. Andrews
article en

Abstract

In this wide-ranging interview David McCall, Senior Editor, BioInsights, and Ben Andrews, Senior Manager in Strategic External Development, GlaxoSmithKline, discuss the key challenges and opportunities for successful oligonucleotide manufacturing at scale, the merits and drawbacks of various synthesis options, and current efforts to mitigate the industry’s environmental impact.

Nucleic Acid InsightsVol. 1(9)
GlaxoSmithKline (United Kingdom) (GB), Age UK (GB)
Openalex Percentile: Top 78%
Chemistry and Chemical Engineering
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