Tackling the key challenges for therapeutic oligonucleotide manufacture: cost, scale, and sustainability
In this wide-ranging interview David McCall, Senior Editor, BioInsights, and Ben Andrews, Senior Manager in Strategic External Development, GlaxoSmithKline, discuss the key challenges and opportunities for successful oligonucleotide manufacturing at scale, the merits and drawbacks of various synthesis options, and current efforts to mitigate the industry’s environmental impact.
Authors
- B. J. Andrews (ORCID: https://orcid.org/0000-0001-9928-1225)
Institutions
- GlaxoSmithKline (United Kingdom) (GB)
- Age UK (GB)
Publication Details
- Journal
- Nucleic Acid Insights
- Published
- 2024-11-26
- DOI
- https://doi.org/10.18609/nai.2024.041
- Primary Topic
- Chemistry and Chemical Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00