Comprehensive analysis of the biological functions and prognostic significance of GDI1 in breast cancer

GDI1 is highly expressed in BRCA and is significantly associated with poor patient prognosis. Its expression level influences the tumor immune microenvironment, and low methylation status indicates worse clinical outcomes. These findings suggest that GDI1 may serve as a potential biomarker for prognosis assessment and immune regulation in BRCA, providing new directions for targeted therapy.

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Publication Details

Journal
Medicine
Published
2025-12-12
DOI
https://doi.org/10.1097/md.0000000000046254
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive analysis of the biological functions and prognostic significance of GDI1 in breast cancer

Zhe Yang, Y Q Zhang, Ning Wang, Huaixi Zhang
Medicine
Ferroptosis and cancer prognosis
article

Comprehensive analysis of the biological functions and prognostic significance of GDI1 in breast cancer

Zhe Yang, Y Q Zhang, Ning Wang, Huaixi Zhang
article en

Abstract

GDI1 is highly expressed in BRCA and is significantly associated with poor patient prognosis. Its expression level influences the tumor immune microenvironment, and low methylation status indicates worse clinical outcomes. These findings suggest that GDI1 may serve as a potential biomarker for prognosis assessment and immune regulation in BRCA, providing new directions for targeted therapy.

MedicineVol. 104(50)
Harbin Medical University (CN), Third Affiliated Hospital of Harbin Medical University (CN)
Openalex Percentile: Top 41%
Ferroptosis and cancer prognosis
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