Research on the potential mechanisms of propofol in treating depression after brain injury based on network pharmacology

This study sheds light on the possible mechanisms by which propofol affects depression in the aftermath of brain injury. Future studies should utilize a network pharmacology framework to explore further the corresponding targets and pathways implicated in the therapeutic effect of propofol on depression after brain injury.

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Publication Details

Journal
Medicine
Published
2025-12-12
DOI
https://doi.org/10.1097/md.0000000000046463
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
0.00
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article

Research on the potential mechanisms of propofol in treating depression after brain injury based on network pharmacology

Qiu‐Xia Xiao, Liu‐Lin Xiong, Binbin Xie, Fei Liu et al.
Medicine
Traumatic Brain Injury and Neurovascular Disturbances
article

Research on the potential mechanisms of propofol in treating depression after brain injury based on network pharmacology

Qiu‐Xia Xiao, Liu‐Lin Xiong, Binbin Xie, Fei Liu, Feng-Ting Ma
article en

Abstract

This study sheds light on the possible mechanisms by which propofol affects depression in the aftermath of brain injury. Future studies should utilize a network pharmacology framework to explore further the corresponding targets and pathways implicated in the therapeutic effect of propofol on depression after brain injury.

MedicineVol. 104(50)
Zunyi Medical University (CN), Sichuan University (CN), West China Hospital of Sichuan University (CN), First People’s Hospital of Zunyi (CN), Second People’s Hospital of Yibin (CN)
Openalex Percentile: Top 45%
Traumatic Brain Injury and Neurovascular Disturbances
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