Anesthetic Management of a Pediatric Patient with Rubinstein–Taybi Syndrome Undergoing Entropion Correction Surgery: A Case Report

Rubinstein–Taybi syndrome (RTS) is a rare genetic disorder that presents unique anesthetic challenges, including a high likelihood of difficult airway management and an increased risk of arrhythmias associated with certain medications. We report the anesthetic management of a 2-year-old patient with RTS undergoing entropion correction surgery. Cisatracurium was selected over rocuronium to reduce the potential for cardiovascular complications, and reversal agents were deliberately avoided due to concerns about arrhythmogenic risk. The pre-administration of lidocaine during induction and before extubation, along with continuous quantitative neuromuscular monitoring throughout the procedure, contributed to a smooth extubation and stable postoperative recovery. This case emphasizes the importance of individualized anesthetic strategies that prioritize safety and cost-effectiveness. It also highlights the critical roles of appropriate muscle relaxant selection, maintenance of hemodynamic stability, timely lidocaine administration, and the use of neuromuscular monitoring in optimizing perioperative outcomes for patients with RTS.

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Publication Details

Journal
Journal of Medical Sciences
Published
2025-12-12
DOI
https://doi.org/10.4103/jmedsci.jmedsci_104_25
Primary Topic
Congenital limb and hand anomalies
Type
article
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article

Anesthetic Management of a Pediatric Patient with Rubinstein–Taybi Syndrome Undergoing Entropion Correction Surgery: A Case Report

Ying-Chun Lu, Yufan Wang, Ke-Hung Chien, Chun-Chang Yeh
Journal of Medical Sciences
Congenital limb and hand anomalies
article

Anesthetic Management of a Pediatric Patient with Rubinstein–Taybi Syndrome Undergoing Entropion Correction Surgery: A Case Report

Ying-Chun Lu, Yufan Wang, Ke-Hung Chien, Chun-Chang Yeh
article en

Abstract

Rubinstein–Taybi syndrome (RTS) is a rare genetic disorder that presents unique anesthetic challenges, including a high likelihood of difficult airway management and an increased risk of arrhythmias associated with certain medications. We report the anesthetic management of a 2-year-old patient with RTS undergoing entropion correction surgery. Cisatracurium was selected over rocuronium to reduce the potential for cardiovascular complications, and reversal agents were deliberately avoided due to concerns about arrhythmogenic risk. The pre-administration of lidocaine during induction and before extubation, along with continuous quantitative neuromuscular monitoring throughout the procedure, contributed to a smooth extubation and stable postoperative recovery. This case emphasizes the importance of individualized anesthetic strategies that prioritize safety and cost-effectiveness. It also highlights the critical roles of appropriate muscle relaxant selection, maintenance of hemodynamic stability, timely lidocaine administration, and the use of neuromuscular monitoring in optimizing perioperative outcomes for patients with RTS.

Journal of Medical SciencesVol. 46(1)
National Defense Medical Center (TW)
Openalex Percentile: Top 62%
Congenital limb and hand anomalies
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Anesthetic Management of a Pediatric Patient with Rubinstein–Taybi Syndrome Undergoing Entropion Correction Surgery: A Case Report — Ying-Chun Lu, Yufan Wang, et al. · Journal of Medical Sciences (2025) | TGRS Research Map | TGRS