Perianal Langerhans cell hyperplasia characterized by perianal ulcerative lesions after hemorrhoid surgery: A case report
This case highlights that perianal LCH can masquerade as a nonhealing surgical wound. Its diagnosis requires a high index of suspicion and timely biopsy with immunohistochemical confirmation. Early and accurate diagnosis is crucial for initiating appropriate systemic evaluation and individualized management, which must carefully balance treatment efficacy with patient tolerance to prevent the morbidity associated with progressive multisystem disease.
Authors
- Han Yu (ORCID: https://orcid.org/0000-0001-6160-173X)
- Dan Huang (ORCID: https://orcid.org/0000-0001-6125-1071)
- Hua Duan (ORCID: https://orcid.org/0000-0002-9428-7561)
- Jitao Fu
- Shubo Gao (ORCID: https://orcid.org/0009-0003-9629-4671)
- Li Zheng (ORCID: https://orcid.org/0000-0003-0971-0343)
- Wenbo Zheng
Institutions
- Affiliated Hospital of Jining Medical University (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1097/md.0000000000046381
- Primary Topic
- Genital Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00