Dexmedetomidine versus ketamine for preemptive caudal analgesia in single-level lumbar laminectomy: A randomized controlled trial

Dexmedetomidine provides superior postoperative analgesia and pain control in the immediate postoperative period compared to ketamine. However, both drugs showed comparable efficacy at later postoperative times, indicating ketamine remains an option for pain management in certain circumstances.

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Publication Details

Journal
Medicine
Published
2025-12-12
DOI
https://doi.org/10.1097/md.0000000000045740
Primary Topic
Treatment of Major Depression
Type
article
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article

Dexmedetomidine versus ketamine for preemptive caudal analgesia in single-level lumbar laminectomy: A randomized controlled trial

Khadiga Ahmed Ismail, Osama Allam Mandour, Hend Abdelmonem Elsakhawy, Nevine M. El-Deeb et al.
Medicine
Treatment of Major Depression
article

Dexmedetomidine versus ketamine for preemptive caudal analgesia in single-level lumbar laminectomy: A randomized controlled trial

Khadiga Ahmed Ismail, Osama Allam Mandour, Hend Abdelmonem Elsakhawy, Nevine M. El-Deeb, Ahmed M.A. El Naggar, Mohammed Majrashi, Gihan Eissa Zahran, Amira Sobhy Khalil Eldeeb, Nashwa Mohammed Ibrahiem, Hend Mostafa Ahmed Abosaifa, Mostafa M. El-Sayed, Mohammed Saad, Wafaa Ali Abd Elhadi, Ahmed Mohammed Ragab, Mohamed Hassan, Mahmoud Mostafa Elshamy, Samy Mohy Eldin, Tarek Adly Aboubakr
article en

Abstract

Dexmedetomidine provides superior postoperative analgesia and pain control in the immediate postoperative period compared to ketamine. However, both drugs showed comparable efficacy at later postoperative times, indicating ketamine remains an option for pain management in certain circumstances.

MedicineVol. 104(50)
Taif University (SA), Al-Azhar University (EG), Zagazig University (EG), University of Jeddah (SA), Al Baha University (SA), Fayoum University (EG)
Openalex Percentile: Top 57%
Treatment of Major Depression
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Dexmedetomidine versus ketamine for preemptive caudal analgesia in single-level lumbar laminectomy: A randomized controlled trial — Khadiga Ahmed Ismail, Osama Allam Mandour, et al. · Medicine (2025) | TGRS Research Map | TGRS