Screening for Celiac Disease in Childhood: Cost-effectiveness of Multiple Genetic and Serological Testing Approaches
The most cost-effective screening strategy for celiac disease was single-time untargeted serological testing at age 11. The optimal approach is affected by regional factors and may evolve with new evidence. Repeated screening may be preferable for high-risk groups and with high willingness to pay.
Authors
- Paula Heikkilä (ORCID: https://orcid.org/0000-0002-5989-8615)
- Jutta E. Laiho (ORCID: https://orcid.org/0000-0002-5443-4651)
- Heikki Hyöty (ORCID: https://orcid.org/0000-0003-0370-4145)
- Katri Lindfors (ORCID: https://orcid.org/0000-0001-7417-5151)
- Laura Kivelä (ORCID: https://orcid.org/0000-0001-7959-7628)
- Jyri Rökman
- Johanna M. Mäkinen (ORCID: https://orcid.org/0000-0001-6129-7272)
- Kalle Kurppa (ORCID: https://orcid.org/0000-0003-4757-2164)
- Frank Emmert‐Streib (ORCID: https://orcid.org/0000-0003-0745-5641)
- Jukka Ranta (ORCID: https://orcid.org/0000-0002-3057-6022)
- Juha Pajula (ORCID: https://orcid.org/0000-0003-0563-6406)
- Ketil Størdal (ORCID: https://orcid.org/0000-0001-7826-8646)
- Khaoula El Mekkaoui
Institutions
- Oslo University Hospital (NO)
- Tampere University (FI)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Fimlab (Finland) (FI)
- VTT Technical Research Centre of Finland (FI)
- Aalto University (FI)
Publication Details
- Journal
- Clinical Gastroenterology and Hepatology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.cgh.2025.11.030
- Citations
- 1
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.81