Untargeted metabolomics based on LC-MS and GC-MS reveal metabolic reprogramming and putative biomarkers in amyotrophic lateral sclerosis
The disturbed pathways and biomarker candidates identified in this study may provide novel insights into ALS pathogenesis and improve diagnostic strategies.
Authors
- Qinming Zhou (ORCID: https://orcid.org/0000-0001-6211-0588)
- Sheng Chen (ORCID: https://orcid.org/0000-0001-7428-7153)
- Long Niu
- Tianbai Li (ORCID: https://orcid.org/0000-0002-8554-6373)
- Guowang Xu (ORCID: https://orcid.org/0000-0003-4298-3554)
- Xiaojie Zhang (ORCID: https://orcid.org/0000-0001-6129-9964)
- Xiaojiao Xu
- Yaping Shao (ORCID: https://orcid.org/0000-0002-8469-9036)
- Weidong Le
Institutions
- University of Electronic Science and Technology of China (CN)
- Dalian Institute of Chemical Physics (CN)
- Dalian Medical University (CN)
- Sichuan University (CN)
- Ruijin Hospital (CN)
- Sir Run Run Shaw Hospital (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Shanghai Sixth People's Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1097/cm9.0000000000003874
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00