Biophysical Mechanisms and Clinical Potential of Millimeter-Wave Therapy in Aesthetic Medicine

Electromagnetic waves in the extremely high frequency (EHF, 30–300 GHz) range represent a non-thermal physical factor with pronounced bioregulatory effects. Their interaction with cellular structures is predominantly informational in nature and is realized through modulation of membrane protein activity, ion channels, and water structuring. These effects find practical application in cosmetology, where the key objectives are the deceleration of age-related skin changes and the acceleration of regeneration following aesthetic procedures. This article considers 2 principal directions for the use of EHF irradiation: slowing the aging of the facial and neck skin by stimulating proliferation of keratinocytes and fibroblasts, activating collagen synthesis and antioxidant mechanisms; accelerating wound healing after plastic surgery, including shortened epithelialization time, reduced inflammatory response, and minimized risk of hypertrophic scarring. Experimental and clinical data are presented, demonstrating the effects of EHF exposure on cellular renewal, microcirculation, and tissue regeneration. Particular attention is given to the prospects of integrating EHF therapy into comprehensive cosmetology protocols, including its combination with laser, phototherapeutic, and injectable methods. Thus, EHF irradiation is viewed as a promising tool in aesthetic medicine, capable of enhancing the efficacy of cosmetic procedures, expediting recovery after surgical interventions, and contributing to a more “natural” external result.