Rising Prevalence of Central Nervous System Involvement in Multiple Myeloma: A 2012-2020 National Inpatient Sample (NIS) Analysis in the United States

The prevalence of CNS-MM has grown to 2%-3% of MM patients since 2020, with stable rates of mortality despite interventions. Further investigation is needed to explore underlying mechanisms of this growth and improve outcomes.

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Publication Details

Journal
Clinical Lymphoma Myeloma & Leukemia
Published
2025-12-01
DOI
https://doi.org/10.1016/j.clml.2025.12.004
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Rising Prevalence of Central Nervous System Involvement in Multiple Myeloma: A 2012-2020 National Inpatient Sample (NIS) Analysis in the United States

Frederick Lansigan, Parth Shah, Jennifer Hong, V. Natarajan et al.
Clinical Lymphoma Myeloma & Leukemia
Multiple Myeloma Research and Treatments
article

Rising Prevalence of Central Nervous System Involvement in Multiple Myeloma: A 2012-2020 National Inpatient Sample (NIS) Analysis in the United States

Frederick Lansigan, Parth Shah, Jennifer Hong, V. Natarajan, Charles J. Mazof, Augustos Vrattos
article en

Abstract

The prevalence of CNS-MM has grown to 2%-3% of MM patients since 2020, with stable rates of mortality despite interventions. Further investigation is needed to explore underlying mechanisms of this growth and improve outcomes.

Clinical Lymphoma Myeloma & Leukemia
Dartmouth College (US), Dartmouth–Hitchcock Medical Center (US)
Openalex Percentile: Top 40%
Multiple Myeloma Research and Treatments
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