Amebic Liver Abscess: An Unusual Cause of Budd–Chiari Syndrome

Amebiasis is a significant public health issue in tropical regions, with liver abscess as its most common extraintestinal complication. Budd-Chiari syndrome secondary to amoebic liver abscess is rare and seldom reported. We present a 37-year-old man with poorly controlled Type 1 diabetes who developed fever, abdominal pain and distension. Imaging identified a left lobe liver abscess with hepatic vein and inferior vena cava thrombosis, consistent with Budd-Chiari syndrome. The patient received image-guided drainage, broad-spectrum antimicrobials, and anticoagulation, leading to clinical improvement and vascular recanalization. We intend to bring to notice, the need to consider hepatic venous outflow obstruction in patients with amoebic liver abscess and ascites or lower extremity edema. Early diagnosis and combined medical and interventional management can help prevent irreversible liver damage.