Precision in production: optimizing monitoring and quality control for high-value plasmids

Gene therapy analytics directly influence product quality, ultimately saving precious time and resources. However, traditional UV spectroscopy, commonly used for bioprocess analytics, can pose a range of challenges. This poster introduces a streamlined analytics process for gene therapy products utilizing variable pathlength technology (VPT) in place of traditional analytical tools. Case study data demonstrates that VPT-based technology can accurately determine pDNA purity ratios in human gene therapy products, automating the R-value calculations and eliminating the need for dilutions.