Producing MSC-derived cell therapies: workflows, technologies, and case studies

In this expert roundtable, four highly experienced industry professionals discuss key considerations in mesenchymal stem (or stromal) cell (MSC) manufacturing, including reagent selection, dosing, delivery methods, and final product formulation. The panelists also explore emerging modalities such as induced pluripotent stem cell (iPSC)-derived MSCs, gene-engineered MSCs, and exosome-based therapies, and emphasize the need for cost reduction and scalable manufacturing to improve accessibility and clinical success.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2025-03-28
DOI
https://doi.org/10.18609/cgti.2025.040
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
0.00
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article

Producing MSC-derived cell therapies: workflows, technologies, and case studies

William C. Wilson, Tung-yuen Ting, Shirley H. J. Mei, Irana Malaspina
Cell and Gene Therapy Insights
Mesenchymal stem cell research
article

Producing MSC-derived cell therapies: workflows, technologies, and case studies

William C. Wilson, Tung-yuen Ting, Shirley H. J. Mei, Irana Malaspina
article en

Abstract

In this expert roundtable, four highly experienced industry professionals discuss key considerations in mesenchymal stem (or stromal) cell (MSC) manufacturing, including reagent selection, dosing, delivery methods, and final product formulation. The panelists also explore emerging modalities such as induced pluripotent stem cell (iPSC)-derived MSCs, gene-engineered MSCs, and exosome-based therapies, and emphasize the need for cost reduction and scalable manufacturing to improve accessibility and clinical success.

Cell and Gene Therapy InsightsVol. 11(2)
Corning (United States) (US), Copernicus Therapeutics (United States) (US), Regenerative Medicine Institute (MX)
Openalex Percentile: Top 39%
Mesenchymal stem cell research
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