The promise of antibody-oligonucleotide conjugates for neurological diseases

“To fully unlock their potential, there are a few key breakthroughs that are going to be critical.”Lauren Coyle, Launch Commissioning Editor, Bioconjugation Insights, speaks with Kerstin Hofer, Science and People Lead, Roche, about the evolving application of antibody-oligonucleotide conjugates in neurology. She highlights their design, delivery challenges across the blood–brain barrier, and potential to transform CNS diseases.

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Publication Details

Journal
Bioconjugation Insights
Published
2025-08-27
DOI
https://doi.org/10.18609/bci.2025.018
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.00

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article

The promise of antibody-oligonucleotide conjugates for neurological diseases

K. G. Hofer
Bioconjugation Insights
HER2/EGFR in Cancer Research
article

The promise of antibody-oligonucleotide conjugates for neurological diseases

K. G. Hofer
article en

Abstract

“To fully unlock their potential, there are a few key breakthroughs that are going to be critical.”Lauren Coyle, Launch Commissioning Editor, Bioconjugation Insights, speaks with Kerstin Hofer, Science and People Lead, Roche, about the evolving application of antibody-oligonucleotide conjugates in neurology. She highlights their design, delivery challenges across the blood–brain barrier, and potential to transform CNS diseases.

Bioconjugation InsightsVol. 1(3)
Roche (Switzerland) (CH)
Roche, F. Hoffmann-La Roche
Openalex Percentile: Top 44%
HER2/EGFR in Cancer Research
DOIOpen Access PDFOpenAlex
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The promise of antibody-oligonucleotide conjugates for neurological diseases — K. G. Hofer · Bioconjugation Insights (2025) | TGRS Research Map | TGRS