Enhancing mRNA results through strategic RNA design and quality control
“There are several design elements known to improve stability and longevity of mRNA in cells while also reducing innate immunogenicity...”In the last few years, mRNA has moved to the fore in the vaccine and cell and gene therapy fields, and as a result, its successful production for these downstream applications has never been more crucial. In this podcast episode, Róisín McGuigan, Editor, Nucleic Acid Insights, speaks to Ryan Lahr, Senior R&D Scientist, CELLSCRIPT, about design, production, and quality control of synthesized mRNA for translation in cells.
Authors
- Ryan Lahr
Institutions
- University of Wisconsin System (US)
Publication Details
- Journal
- Nucleic Acid Insights
- Published
- 2025-03-27
- DOI
- https://doi.org/10.18609/nuc.2024.007
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00