CAR-T manufacturing intensification: the next wave of CAR-T commercialization
Since the commercialization of the first CAR-T therapies, these revolutionary treatments have reshaped the landscape of cancer therapy, offering unprecedented hope to patients with hematologic malignancies. Here, a panel of industry and healthcare sector experts to discuss the critical intersection of commercialization strategies and manufacturing technology in advancing the next wave of CAR-T therapies to market. They explore the current industry status and the latest innovations that have the potential to optimize manufacturing processes for scale-up or scale-out, impacting cost of goods (CoGs) and manufacturing success to meet the growing demand and ensure broader patient access.
Authors
- Paul Bowles (ORCID: https://orcid.org/0000-0001-7714-772X)
- Alexey Bersenev (ORCID: https://orcid.org/0000-0003-1442-0009)
- Emilie Kleiren
- John Knighton
Institutions
- Johnson & Johnson (United States) (US)
- Yale University (US)
- ASIT Biotech (Belgium) (BE)
- Ontario Medical Association (CA)
Publication Details
- Journal
- Cell and Gene Therapy Insights
- Published
- 2025-04-03
- DOI
- https://doi.org/10.18609/cgti.2025.034
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00