CAR-T manufacturing intensification: the next wave of CAR-T commercialization

Since the commercialization of the first CAR-T therapies, these revolutionary treatments have reshaped the landscape of cancer therapy, offering unprecedented hope to patients with hematologic malignancies. Here, a panel of industry and healthcare sector experts to discuss the critical intersection of commercialization strategies and manufacturing technology in advancing the next wave of CAR-T therapies to market. They explore the current industry status and the latest innovations that have the potential to optimize manufacturing processes for scale-up or scale-out, impacting cost of goods (CoGs) and manufacturing success to meet the growing demand and ensure broader patient access.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2025-04-03
DOI
https://doi.org/10.18609/cgti.2025.034
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

CAR-T manufacturing intensification: the next wave of CAR-T commercialization

Paul Bowles, Alexey Bersenev, Emilie Kleiren, John Knighton
Cell and Gene Therapy Insights
CAR-T cell therapy research
article

CAR-T manufacturing intensification: the next wave of CAR-T commercialization

Paul Bowles, Alexey Bersenev, Emilie Kleiren, John Knighton
article en

Abstract

Since the commercialization of the first CAR-T therapies, these revolutionary treatments have reshaped the landscape of cancer therapy, offering unprecedented hope to patients with hematologic malignancies. Here, a panel of industry and healthcare sector experts to discuss the critical intersection of commercialization strategies and manufacturing technology in advancing the next wave of CAR-T therapies to market. They explore the current industry status and the latest innovations that have the potential to optimize manufacturing processes for scale-up or scale-out, impacting cost of goods (CoGs) and manufacturing success to meet the growing demand and ensure broader patient access.

Cell and Gene Therapy InsightsVol. 11(2)
Johnson & Johnson (United States) (US), Yale University (US), ASIT Biotech (Belgium) (BE), Ontario Medical Association (CA)
Openalex Percentile: Top 44%
CAR-T cell therapy research
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