Opioid-free anesthesia with esketamine combined with interpectoral plane block and pectoralis-serratus plane blocks in radical mastectomy: a randomized controlled trial
For patients undergoing radical mastectomy, opioid-free anesthesia (OFA) utilizing esketamine combined with Interpectoral Plane (IPP) and Pectoralis-Serratus Plane (PSP) blocks significantly improved postoperative recovery quality compared to conventional opioid-based anesthesia (OA).
Authors
- Youming Deng
- Wenping Ding (ORCID: https://orcid.org/0000-0002-4252-8212)
- Nan Sun (ORCID: https://orcid.org/0000-0001-6812-9917)
- Rongguo Wang (ORCID: https://orcid.org/0000-0002-8448-1862)
- Qian Liu (ORCID: https://orcid.org/0000-0002-1937-0568)
- Yan Liu (ORCID: https://orcid.org/0000-0002-7682-3498)
- Liwei Wang (ORCID: https://orcid.org/0000-0002-5346-5886)
- Yan Zhang (ORCID: https://orcid.org/0000-0001-5583-6428)
- Meiyan Zhou (ORCID: https://orcid.org/0009-0003-7193-9242)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Xuzhou Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.3389/fphar.2025.1679423
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00