Intestinal-Type Adenocarcinoma Is a Rare Histotype of Vulvar Neoplasm: Systematic Review of the Literature
VAIt is a very rare histotype of vulvar cancer. Compared to vulvar squamous cell carcinomas, approximately 40% of early-stage clinical diseases reported in the literature presented positive inguinal lymph nodes with recurrence even after many years. The optimal treatment is not well defined and should be based on the individual clinical history of the patient, as there are no established guidelines. Further studies and longer follow-up periods are needed to clarify the best therapeutic management and its long-term prognosis.
Authors
- Maurizio Guida (ORCID: https://orcid.org/0000-0001-7372-0680)
- Luigi Della Corte (ORCID: https://orcid.org/0000-0002-0584-2181)
- Dominga Boccia (ORCID: https://orcid.org/0009-0008-4151-9470)
- Silvia D’Ippolito (ORCID: https://orcid.org/0000-0002-6160-0558)
- F. Rosato
- Damiano Arciuolo (ORCID: https://orcid.org/0000-0002-3927-985X)
- Maria De Ninno
- Francesco Cosentino (ORCID: https://orcid.org/0000-0002-5698-7946)
- Daniele Neola (ORCID: https://orcid.org/0000-0001-6723-0415)
- Giuseppe Bifulco (ORCID: https://orcid.org/0000-0001-7772-8591)
- Alessio Colalillo (ORCID: https://orcid.org/0009-0001-4834-0974)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Molise (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Cancers
- Published
- 2025-12-14
- DOI
- https://doi.org/10.3390/cancers17243989
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00