The Prognosis of Males and Females With Moderate or Severe Secondary Mitral Valve Regurgitation and Avenues for Improvement
Overall survival in patients with SMR was low with an estimated 5-year survival of 70%. Females had a better survival in patients with SMR than males. The lower survival in males with SMR might be due to a larger proportion of atrial SMR in females, fewer patients with ischemic SMR, and lower ejection fractions in males with non-ischemic SMR. The current focus on rapid heart failure medication optimization may improve the prognosis of the most vulnerable group; future studies can be directed to see whether this will be the case.
Authors
- Jelle P. Man (ORCID: https://orcid.org/0000-0003-2040-3686)
- Steven A. J. Chamuleau (ORCID: https://orcid.org/0000-0002-9952-6701)
- Berto J. Bouma (ORCID: https://orcid.org/0000-0002-1433-9692)
- Mark J. Schuuring (ORCID: https://orcid.org/0000-0002-2843-1852)
- M. A. Molenaar
Institutions
- Medisch Spectrum Twente (NL)
- Netherlands Heart Institute (NL)
- Amsterdam University Medical Centers (NL)
- University of Twente (NL)
Publication Details
- Journal
- Echocardiography
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/echo.70370
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00